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Assessment of Neurological Prognosis in Comatose Survivors of Cardiac Arrest Lancet 343:1055-1059, Edgren,E.,et al, 1994 See this aricle in Pubmed Article Abstract Glasgow and Glasgow-Pittsburgh coma scores and their constituent signs were recorded at fixed times.Outcome was taken to be the best cerebral performance at any time during follow-up,and for that purpose we used cerebral performance categories(CPC 1-5)of the Glasgow outcome categories. A poor outcome(CPC 3-5)could be predicted immediately after reperfusion(at entry into the study)with an accuracy ranging from 52%to 84%for various signs and scores.On the third day it was possible to identify severely disabled or permanently comatose survivors without false predictions using both coma scores and several of their constituent variables.The best predictor was absence of motor response to pain.This modeling exercise now needs to be repeated on a new series of patients but the results do suggest that,after 3 days,stringent ethical criteria can be met and used in decision-making about termination of care in comatose cardiac arrest survivors.

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(click to filter results - removes previous filter) cardiac arrest cardiac arrest and resuscitation coma coma,prognosis of ethics in neurology Glasgow coma score hypoxic encephalopathy life support,withdrawal of neurologic examination prognosis

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